Canadian medical patient and activist David Reimer was BOTD in 1965. Born Bruce Reimer in Winnipeg, Manitoba to a working-class couple of Mennonite descent, his penis was severely damaged after a botched medical circumcision when he was seven months old. In 1967, his parents took David to consult with Dr John Money at Johns Hopkins Hospital in Baltimore, at the time considered an industry leader in child sexual development. Money persuaded the Reimers that gender reassignment surgery was David’s best option for a normal life. At the age of 22 months, David underwent surgery to remove his testes and have an artificial vulva constructed from his remaining genital tissue. He was subsequently named Brenda and raised as female. Money became a medical superstar after reporting the success of the “John/John Case”, which he used to advance his theories of gender as a purely socially-learned concept. David and his twin brother Brian continued to see Money for medical consultations, in which Money forced them to strip naked, fondle each other’s genitals and act out “sexual rehearsal play”, with David taking the “passive” feminine role. As he reached adolescence, David was given estrogen injections to promote breast development. After years of psychological distress, the 13 year-old Reimer refused to see Money again, and his parents told him the truth about his gender reassignment. The following year, he adopted a male identity, calling himself David, and underwent surgery to remove his breasts and restore his male genitalia. In 1990, he married Jane Fontaine, with whom he raised her three children from a previous relationship. His case came to international attention in 1997, when sexologist Milton Diamond persuaded him to reveal his identity and discredit Money’s work. His story shocked the medical establishment, and reached a wider audience via an article by Rolling Stone John Colapinto. With Reimer’s consent, Colapinto expanded his article into the 2000 biography As Nature Made Him: The Boy Who Was Raised as a Girl, which became a New York Times bestseller. The renewed publicity further destabilised the Reimers’ mental health. In 2002, Brian committed suicide via a drug overdose. David subsequently lost his job, fell deeply into debt and separated from Fontaine. He shot himself in 2004, aged 38. Despite the controversy, Money continued to promote medical interventions for intersex children, retaining his medical licence and academic tenure until his death in 2006.